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References

  1. P Aragona et al., “Systemic Omega-6 essential fatty acid treatment and pge1 tear content in Sjögren’s syndrome patients,” Invest Ophthalmol Vis Sci., 46, 4474 (2005). DOI:10.1167/iovs.04-1394 
  2. R Kapoor, YS Huang, “Gamma linolenic acid: an antiinflammatory omega-6 fatty acid,” Curr Pharm Biotechnol., 7, 531 (2006). DOI:10.2174/138920106779116874.
  3. A Pinna et al., “Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction,” Cornea, 26, 260 (2007). DOI:10.1097/ICO.0b013e318033d79b.
  4. F Brignole-Baudouin et al., “A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients,” Acta Ophthalmol., 89, 591 (2011). DOI: 10.1111/j.1755-3768.2011.02196.x.
  5. JD Sheppard Jr et al., “Long-term supplementation with n-6 and n-3 PUFAs improves moderate-to-severe keratoconjunctivitis sicca: a randomized double-blind clinical trial,” Cornea, 32, 1297 (2013). DOI:10.1097/ICO.0b013e318299549c

Eric T. Brooker

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